Ariessence PDGF vs. PRF + ACell: Which Hair Regeneration Treatment is Right for You?
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Hair Restoration Showdown: Ariessence PDGF vs. PRF + ACell
If you’re starting to notice thinning hair or early signs of hair loss, you’re not alone — and the good news is that regenerative aesthetic medicine offers powerful, non-surgical solutions to help restore hair growth naturally.
At Whitefish Creative Aesthetics, two of our most popular options are Ariessence PDGF and PRF with ACell. But what’s the difference between them? Read further as we break it down!
What is Ariessence PDGF?
Ariessence PDGF is a lab-derived serum rich in Platelet-Derived Growth Factor (PDGF), one of the key molecules responsible for tissue repair and hair follicle stimulation.
Because it’s created in a controlled environment, Ariessence PDGF provides a consistent dose of regenerative factors without requiring a blood draw.
Key Benefits:
- Stimulates hair follicle activity and improves blood flow to the scalp
- No blood draw needed — a great choice for patients with low platelet counts or certain medical conditions
- Fast and easy application
Ideal for:
Patients seeking a quick, low-maintenance treatment who prefer not to use autologous (self-derived) products.
What is PRF + ACell?
PRF (Platelet-Rich Fibrin) is a second-generation, all-natural platelet concentrate made directly from your own blood. It’s rich in a wide variety of growth factors like PDGF, VEGF, and TGF-β, and it creates a fibrin matrix that slowly releases these factors over time for sustained regeneration.
We pair PRF with ACell, a regenerative extracellular matrix product derived from pig bladder tissue. ACell acts as a biological scaffold, encouraging stronger tissue repair and hair follicle rejuvenation.
Key Benefits:
- Completely natural, using your own body’s healing abilities
- Provides a sustained release of growth factors for longer-lasting results
- ACell enhances repair and regeneration at a deeper level
- Ideal for thinning, shedding, or early-stage hair loss
Ideal for:
Patients seeking a comprehensive, natural solution with longer-term benefits.
Side-by-Side Comparison:
Feature | Ariessence PDGF | PRF + ACell |
Source | Lab-created growth factors | Patient’s own blood + regenerative scaffold |
Treatment Process | No blood draw | Blood draw + advanced preparation |
Growth Factors | Primarily PDGF | Multiple: PDGF, VEGF, TGF-β, and more |
Healing Matrix | No | Yes (Fibrin + ACell) |
Best For | Quick regeneration, no downtime | Deep repair, longer-lasting hair growth support |

Which Hair Restoration Option is Right for You?
Both Ariessence PDGF and PRF + ACell are excellent choices, depending on your goals, timeline, and personal preferences.
If you’re unsure which path is best, don’t worry — our expert team is here to guide you every step of the way.
✨ Book your consultation today and let’s create a personalized hair restoration plan that works for you!